Panthers coach Ivan Cleary has finalised his side to face Manly Sea Eagles at Panthers Stadium.
Viliame Kikau is a late withdrawal due to illness with Liam Martin promoted from the reserves into the starting side.
Mitch Kenny will start at hooker with Sione Katoa dropping back to the bench, while Tim Grant starts in place of Reagan Campbell-Gillard.
Caleb Aekins has been omitted and will play for the Panthers Canterbury Cup side against Blacktown Workers.
The Panthers will wear the 2019 Home Jersey and 23-year-old centre Brent Naden will make his NRL debut as Panther No.587.
Panthers v Sea Eagles
7.50pm Thursday 30 May
1. Dylan EDWARDS - sponsored by Lendcorp
2. Josh MANSOUR - sponsored by Daily Press
3. Isaah YEO - sponsored by Volvo Cars Penrith
4. Brent NADEN - sponsored by AMA Event Management
5. Brian TO'O - sponsored by Fornari's Interior Linings
6. Jarome LUAI - sponsored by Soneta Plumbing
7. James MALONEY - sponsored by Tuff Mouthguards
8. James TAMOU (c) - sponsored by Signace
14. Mitch KENNY - sponsored by Hertz
17. Tim GRANT - sponsored by HIX Group
21. Liam MARTIN - sponsored by Zoo Fitness
12. Frank WINTERSTEIN - sponsored by Chemtools
13. James FISHER-HARRIS - sponsored by Stylus Blinds
9. Sione KATOA - sponsored by Chardon & Abbott Home Loans
15. Tyrell FUIMAONO - sponsored by Protech Locksmiths
16. Moses LEOTA - sponsored by Potter Automotive
10. Reagan CAMPBELL-GILLARD - sponsored by Bidfood