Panthers coach Ivan Cleary has named his squad to face Parramatta Eels at BlueBet Stadium on Friday.
The match will be played behind closed doors as a result of the NSW Government COVID-19 stay-at-home order for Greater Sydney.
Nathan Cleary (shoulder), Dylan Edwards (foot), Robert Jennings (hamstring) and Paul Momirovski (hip) are all unavailable for selection due to injury.
Panthers will provide more information about the extent of Cleary's shoulder injury on Wednesday, following his return to the Panthers NRL bubble and assessment by club medical staff.
Jarome Luai will play halfback against the Eels with Matt Burton at five-eighth, Charlie Staines shifts to fullback, Brent Naden makes his return on the wing and Viliame Kikau is back from a hamstring injury.
The Panthers will wear the 2021 Home Jersey.
Round 16: NRL Teamlist Video
Match: Panthers v Eels
Round 16 -
Venue: BlueBet Stadium, Penrith
1. Charlie STAINES - sponsored by Soneta Plumbing
2. Brent NADEN - sponsored by Chemtools
3. Stephen CRICHTON - sponsored by Protech Locksmiths
4. Tyrone MAY - sponsored by Hertz
5. Brian TO'O - sponsored by Granville PlastaMasta
6. Matt BURTON - sponsored by Wisdom Dental and Denture Clinic
7. Jarome LUAI - sponsored by CC Tyres Penrith
8. Moses LEOTA - sponsored by East Blaxland Butchery
9. Apisai KOROISAU - sponsored by Casella Express
10. James FISHER-HARRIS - sponsored by Hix Group
11. Viliame KIKAU - sponsored by Fornari's Interior Linings
12. Kurt CAPEWELL - sponsored by MKJ Projects
13. Isaah YEO (c) - sponsored by Chardon & Abbott Home Loans
14. Mitch KENNY - sponsored by Wright Way Plumbing & Civil
15. Scott SORENSEN - sponsored by Cetnaj Wetherill Park
16. Spencer LENIU - sponsored by Potter Automotive
17. Liam MARTIN - sponsored by El Gringos Locos
18. Izack TAGO - sponsored by Stylus Blinds
19. Jaeman SALMON - sponsored by Uphire
20. Matt EISENHUTH - sponsored by Lonestar Rib House & Brews Penrith
21. Taylan MAY - sponsored by You. Me. Brand. Now.