Panthers coach Ivan Cleary has finalised his side to face Gold Coast Titans at Cbus Super Stadium.
Tyrone May has been promoted to the starting side, with Billy Burns dropping back to the bench, after Viliame Kikau was earlier ruled out with a minor calf injury.
The Panthers will field the competition's least experienced line-up, with only 968 combined NRL games between the 17 players.
Kikau joins Dylan Edwards (hamstring), Api Koroisau (elbow), Dean Whare (thigh), Brian To'o (ankle), Kurt Capewell (knee), Zane Tetevano (back) and Jed Cartwright (shoulder) on the sidelines.
The Panthers will wear the pink 2020 Alternate Jersey.
Cleary confident as reserves get their shot
Match: Titans v Panthers
Round 11 -
Venue: Cbus Super Stadium, Gold Coast
1. Caleb AEKINS - sponsored by CC Tyres Penrith
2. Josh MANSOUR - sponsored by MKJ Projects
3. Brent NADEN - sponsored by Potter Automotive
4. Stephen CRICHTON - sponsored by Penrith Toyota
5. Malakai WATENE-ZELEZNIAK - sponsored by Soneta Plumbing
6. Jarome LUAI - sponsored by Hertz
7. Nathan CLEARY - sponsored by Chemtools
8. James TAMOU (c) - sponsored by Protech Locksmiths
9. Mitch KENNY - sponsored by Cetnaj Wetherill Park
10. James FISHER-HARRIS - sponsored by Chardon & Abbott Home Loans
14. Tyrone MAY - sponsored by Hix Group
12. Liam MARTIN - sponsored by AMA Event Management
13. Isaah YEO - sponsored by Casella Express
17. Billy BURNS - sponsored by Signace
15. Spencer LENIU - sponsored by Wisdom Dental and Denture Clinic
16. Moses LEOTA - sponsored by Fornari's Interior Linings
18. Matt BURTON - sponsored by Wright Way Plumbing & Civil