The Panthers will take on Wests Tigers in a Friday double-header at Suncorp Stadium as part of the 2019 Magic Round initiative.
The full 2019 NRL Draw will be revealed on penrithpanthers.com.au at 11am today.
All 16 NRL clubs are scheduled to play in Brisbane in Round 9 as part of a multi-year agreement between the NRL and Queensland State Government.
The action kicks off on Thursday 9 May with Gold Coast Titans taking on Cronulla Sharks.
The Panthers face Wests Tigers at 6pm on Friday 10 May, in what is technically a home game for the Tigers, with Brisbane tackling Manly in the second game at 8pm.
Suncorp Stadium will host three games on Saturday 11 May and the final two Magic Round fixtures on Sunday 12 May.