The Panthers mauled Wests Tigers 36-2 earlier this season in their own backyard at Campelltown Stadium.
A tightly-contested opening half was blown wide open when Dean Whare crossed over before Viliame Kikau and Dylan Edwards bagged their first tries in the NRL to give the Panthers a comfortable lead at the break.
Another try to Whare and further four-pointers to Leilani Latu and Nathan Cleary, who also slotted five goals, sealed a comfortable win for the Panthers.
